Samir Ghosheh was born in Jerusalem in 1937. He received his primary, preparatory, and secondary education in Jerusalem schools, and obtained a bachelor's degree in dentistry from Damascus University in Syria. He became involved in national action from his earliest years, joining the Arab Nationalist Movement in 1967, and was one of the leaders of student activism. In the wake of the June 1967 War, he co-founded, with several of his companions, the Palestinian Popular Struggle Front (PPSF). In 1971, he was elected Secretary-General of PPSF and thanks to his leadership, PPSF joined the Front of the Palestinian Forces Rejecting Solutions of Surrender (the Rejectionist Front), and remained in office until he died in 2009.

The collection contains photographs and documents describing Samir Ghosheh's personal and political life. It documents his visits and the conferences he participated in. It includes handwritten notes of meetings, certificates of good conduct that were issued to Ghosheh in different years of his life, his certificate in dental surgery from the University of Damascus, the text of the presidential decree awarding him the Order of the Star of Jerusalem, his membership cards in addition to postcards for the cover of Nidal Asha'b Magazine.